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Top Medical Research Studies
9
Magnetic stent-grafts improve healing
Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model.
We explored how magnetizable stent-grafts can improve healing in carotid artery pseudoaneurysms by investigating their ability to capture blood outgrowth endothelial cells.
In a porcine model, we compared magnetic stent-grafts with standard non-magnetic ones. The results showed that the magnetic stent-grafts not only occluded all nine pseudoaneurysms but also achieved better cell capture and endothelial growth.
Essentially, the magnetic properties enhanced the healing process, leading to less thrombosis compared to non-magnetic counterparts. This innovative approach could reduce complications associated with these medical devices.
Read More
9
ESA and iron enhance surgery outcomes
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
Read More
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
Read More
Most Useful Reviews
7.5
Improved blood levels
I take this nutritional supplement before bed as it contains vital ingredients for fertility, such as iron and folic acid. My blood tests, which previously indicated anaemia, have shown improved red blood cell levels.
Read More
7.5
Effective iron supplement
1 people found this helpful
Super product! This is the only iron supplement that is truly absorbable and effective, as it has neatly organised my blood. It is well tolerated and does not cause any stomach issues. I recommend it to everyone!
Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia.
We aimed to understand how preoperative treatments like erythropoietin-stimulating agents (ESAs) and intravenous (IV) iron influence the risk of blood clots in surgical patients dealing with anaemia.
In our investigation, we found that patients who received ESAs—whether accompanied by IV iron or not—had lower risks of serious post-operative complications, including blood clots, compared to those who were given red blood cell transfusions. Specifically, those treated with ESAs without IV iron showed significant reductions in mortality and the occurrence of venous thromboembolic events.
Interestingly, when IV iron was combined with ESAs, it appeared to further enhance outcomes, notably improving survival rates. Our results suggest that combining these treatments might yield benefits for patients undergoing surgery, reflected in higher haemoglobin levels and fewer complications compared to traditional blood transfusions.
Read More
9
Magnetic stent-grafts improve healing
Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model.
We explored how magnetizable stent-grafts can improve healing in carotid artery pseudoaneurysms by investigating their ability to capture blood outgrowth endothelial cells.
In a porcine model, we compared magnetic stent-grafts with standard non-magnetic ones. The results showed that the magnetic stent-grafts not only occluded all nine pseudoaneurysms but also achieved better cell capture and endothelial growth.
Essentially, the magnetic properties enhanced the healing process, leading to less thrombosis compared to non-magnetic counterparts. This innovative approach could reduce complications associated with these medical devices.
Read More
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
7.5
Improved blood levels
I take this nutritional supplement before bed as it contains vital ingredients for fertility, such as iron and folic acid. My blood tests, which previously indicated anaemia, have shown improved red blood cell levels.
Read More
7.5
Effective iron supplement
1 people found this helpful
Super product! This is the only iron supplement that is truly absorbable and effective, as it has neatly organised my blood. It is well tolerated and does not cause any stomach issues. I recommend it to everyone!
Read More
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References
Basu R, Reddy M, Kaabneh A, Mohamedelamin Khidir Ahmed A, Bamne S. May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women. Cureus. 2024;16:e75621. 10.7759/cureus.75621
Choi UE, Nicholson RC, Frank SM, Cha S, Cho BC, et al. Use of preoperative erythropoietin-stimulating agents is associated with decreased thrombotic adverse events compared to red blood cell transfusion in surgical patients with anaemia. Vox Sang. 2024;119:1174. 10.1111/vox.13729
Oliver AA, Carlson KD, Price C, Banaskiewicz K, Benike A, et al. Magnetic capture of blood outgrowth endothelial cells to the luminal surface of magnetizable stent-grafts promotes healing in a porcine pseudoaneurysm model. Acta Biomater. 2025. 10.1016/j.actbio.2025.03.040